Does it really matter what time of day when you take supplements such vitamin D, magnesium and vitamin C?

It generally doesn't matter what time of day you take supplements, as long as you are taking them consistently. It is best to take vitamins and minerals with food, as it may reduce digestive upset. Some supplements such as B vitamins may be energizing and should be taken earlier in the day to avoid disruption of sleep.
 
Transcript: "This question is, does it really matter? What time of day? You take supplements such as Vitamin D, magnesium and vitamin C? Look. I've been doing this for 30 years. I've been taking supplements. Have been advising people who take supplements, I have found in general, it doesn't make much difference. There are certain rules of thumb magnesium's very relaxing. You might want to, if you're loading up on magnesium, may be the night times a better time to take that. But you know, the thing is the right time to take vitamins and minerals and supplements. Is when you're likely to take them, you know, that's that's really much more important than the time. The other question, you didn't ask it but I'll throw it out there anyway because a lot of people ask that in conjunction with the time of day question, which is should I take it with or without food? My rule of thumb is, if you don't know, take it with food, less digestive upset, let's likelihood of digestive upset. There are certain times when certain supplements will be prescribed by a health practitioner for a specific reason, and they're meant to be taken away from food. And that's pretty rare. Most of the time we humans got our vitamins and minerals when we ate. So our bodies are very used to taking extra nutrients in, you know, when you're eating so that would be my rule of thumb with with take or take with food or without food and as far as time of day, I don't really think it matters a lot. There are some people who might say that it's not the greatest idea to take the B vitamins at night. I think I'd probably agree with that because they can be energizing particularly if you're deficient in the And then all the sudden you get them and you be awesome energy that you didn't feel before. It's not really the vitamin giving it to you. It's the absence of the deficiency that's giving you that that little kick. But that could happen at night and I probably wouldn't, you know, stock up on my B12 right before bed."